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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
2.12
Human Site:
T560
Identified Species:
3.59
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
T560
S
P
G
S
P
Q
E
T
V
P
E
F
P
C
T
Chimpanzee
Pan troglodytes
XP_509441
819
90122
L530
P
E
F
H
S
S
I
L
V
T
D
L
G
H
G
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
N123
C
R
D
K
I
R
L
N
N
A
I
W
R
A
W
Dog
Lupus familis
XP_546925
857
93734
M565
P
S
G
S
P
Q
E
M
A
P
E
F
P
C
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
S572
E
S
P
Q
D
T
V
S
E
I
P
R
A
R
A
Rat
Rattus norvegicus
Q6AXT8
471
49872
K204
T
H
W
N
R
E
T
K
Q
F
F
L
Q
F
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
V604
S
V
P
D
V
P
A
V
F
L
P
R
V
A
Q
Frog
Xenopus laevis
NP_001084764
548
60887
P281
M
I
Q
P
E
L
F
P
L
Q
P
N
L
D
L
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
T535
L
S
T
D
V
V
S
T
T
G
M
V
I
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
P539
N
S
N
S
N
A
P
P
V
H
Y
A
N
V
T
Honey Bee
Apis mellifera
XP_394429
1014
115124
Q721
I
T
T
P
V
T
V
Q
T
M
Q
T
S
T
V
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
V622
T
S
T
I
F
G
N
V
E
N
K
P
E
R
I
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
T1022
G
S
C
T
P
V
R
T
V
V
F
Q
Q
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
P792
R
A
P
S
A
P
P
P
P
P
P
K
L
G
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
6.6
0
73.3
N.A.
0
0
N.A.
N.A.
6.6
0
6.6
N.A.
20
0
0
20
P-Site Similarity:
100
13.3
13.3
73.3
N.A.
6.6
20
N.A.
N.A.
6.6
6.6
13.3
N.A.
26.6
6.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
8
0
8
8
0
8
8
22
8
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
0
0
0
15
0
% C
% Asp:
0
0
8
15
8
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
8
8
0
0
8
8
15
0
15
0
15
0
8
0
0
% E
% Phe:
0
0
8
0
8
0
8
0
8
8
15
15
0
8
0
% F
% Gly:
8
0
15
0
0
8
0
0
0
8
0
0
8
8
8
% G
% His:
0
8
0
8
0
0
0
0
0
8
0
0
0
8
8
% H
% Ile:
8
8
0
8
8
0
8
0
0
8
8
0
8
0
8
% I
% Lys:
0
0
0
8
0
0
0
8
0
0
8
8
0
0
8
% K
% Leu:
8
0
0
0
0
8
8
8
8
8
0
15
15
0
8
% L
% Met:
8
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% M
% Asn:
8
0
8
8
8
0
8
8
8
8
0
8
8
0
0
% N
% Pro:
15
8
22
15
22
15
15
22
8
22
29
8
15
0
0
% P
% Gln:
0
0
8
8
0
15
0
8
8
8
8
8
15
0
8
% Q
% Arg:
8
8
0
0
8
8
8
0
0
0
0
15
8
15
0
% R
% Ser:
15
43
0
29
8
8
8
8
0
0
0
0
8
0
8
% S
% Thr:
15
8
22
8
0
15
8
22
15
8
0
8
0
8
29
% T
% Val:
0
8
0
0
22
15
15
15
29
8
0
8
8
15
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _